Our dogs are cherished members of our families, and their health is of utmost importance. Hyperlipidemia, or high cholesterol, is a condition that can affect dogs just as it does humans. In this article, we will explore the world of hyperlipidemia in dogs, understanding what it is, its causes, symptoms, diagnosis, treatment, and prevention. If you notice symptoms associated with hyperlipidemia, schedule a visit with your veterinarian to determine the underlying cause. Your vet will want to know a full history of your pet’s health. He may also conduct a physical exam and order tests to help diagnose your dog.
What is Hyperlipidemia?
Hyperlipidemia in dogs refers to the elevated levels of lipids (excess fats) in their bloodstream, specifically cholesterol and triglycerides, known as blood lipids. While some amount of cholesterol is necessary for a dog’s health, an excess can lead to various health problems. Dogs with high blood lipid levels are at risk of developing complications such as pancreatitis and cardiovascular issues. There are two types of hyperlipidemia:
Primary hyperlipidemia is genetic or idiopathic, less common than secondary hyperlipidemia, and may be breed-specific.
Secondary hyperlipidemia, which is more common, is caused by other health conditions and can lead to various complications, including pancreatitis, liver disease, and neurological problems.

Possible Causes of Hyperlipidemia in Dogs
Hyperlipidemia in dogs can be caused by a variety of factors, including genetics, diet, and other underlying health conditions as well as Medication-induced hyperlipidemia. Breeds such as Beagles and Miniature Schnauzers, which have a genetic predisposition to hyperlipidemia, are more prone to this condition. High-fat diets, lack of exercise, and obesity can also contribute to high cholesterol levels in dogs. Some of the causes of high cholesterol may include:
- Genetics: Some dog breeds are genetically predisposed to hyperlipidemia, making them more susceptible to this condition.
- Diet: A high-fat diet, especially one rich in fatty table scraps or excessive treats, can contribute to elevated cholesterol levels in dogs.
- Obesity: Overweight dogs are at an increased risk of developing hyperlipidemia, as excess body fat can lead to disruptions in lipid metabolism.
- Lack of Exercise: Dogs that lead a sedentary lifestyle without sufficient physical activity are more likely to have high cholesterol levels.
- Underlying Health Conditions: Certain medical conditions, such as hypothyroidism, diabetes mellitus or Cushing’s disease, can disrupt a dog’s lipid metabolism and lead to hyperlipidemia.
- Medications: Some medications may have side effects that can impact a dog’s lipid profile, leading to high cholesterol levels.
- Hormonal Changes: Changes in hormonal balance, such as in unspayed or unneutered dogs, can affect lipid metabolism.
- Age: As dogs age, they may become more prone to hyperlipidemia, making regular check-ups and monitoring crucial for senior dogs.
Clinical Signs and Symptoms
Recognizing the signs of hyperlipidemia in dogs is essential for early intervention. Common symptoms include:
- Lethargy
- Vomiting
- Diarrhea
- Abdominal pain
- Loss of appetite
- Yellowing of the eyes and gums (jaundice)
- Hair loss
- Seizures
- Inflammation of the eyes

Diagnosing Hyperlipidemia
Diagnosing hyperlipidemia typically involves a blood test to measure the levels of cholesterol and triglycerides. In addition to measuring total cholesterol and triglycerides, a comprehensive lipid profile may be performed to assess other lipoproteins, such as HDL (high-density lipoprotein) and LDL (low-density lipoprotein). This profile provides a more detailed picture of the dog’s lipid metabolism. Your veterinarian may perform additional testing to rule out underlying conditions that could be contributing to the high lipid levels.
Treatment and Management
The treatment of hyperlipidemia in dogs may involve a multi-faceted approach. This can include dietary changes, exercise, and medications. Your veterinarian will create a customized treatment plan based on your dog’s specific needs.
1. Dietary Considerations
Dietary management plays a crucial role in managing hyperlipidemia. Low-fat, high-fiber diets are often recommended to help lower cholesterol levels. Avoiding table scraps and treats high in fat is essential.
2. Exercise and Weight Management
Regular exercise is key to maintaining a healthy weight and managing cholesterol levels. It’s important to engage your dog in daily physical activity to promote overall well-being.
3. Medications
In some cases, your veterinarian may prescribe medications to help lower cholesterol and triglyceride levels in your dog. Sometimes natural supplements such as fish oil and Chitosan are combined with a high fiber diet. In addition, some human medications may be prescribed such as bezafibrate and gemfibrozil, which can decrease the production of triglycerides and certain cholesterols. These medications should be administered as directed by your vet as they have not been tested extensively for canine use.
Regular check-ups and monitoring of cholesterol levels are vital for dogs with hyperlipidemia. Your veterinarian will guide you on the frequency of follow-up visits.

Complications of Hyperlipidemia
Untreated hyperlipidemia can lead to severe health complications such as:
- Pancreatitis: One of the most significant risks associated with high cholesterol in dogs is the development of pancreatitis. Acute pancreatitis is a painful and potentially life-threatening inflammation of the pancreas. Elevated levels of triglycerides, a type of lipid, are particularly associated with an increased risk of pancreatitis. This condition can lead to severe abdominal pain, vomiting, diarrhea, and, in severe cases, systemic complications that require hospitalization and intensive treatment.
- Cardiovascular Issues: Elevated cholesterol levels in dogs can also contribute to cardiovascular problems, similar to how high cholesterol is linked to heart disease in humans. It can lead to the formation of atherosclerotic plaques in the arteries, potentially reducing blood flow and increasing the risk of heart-related issues. Dogs with high cholesterol may be at risk of conditions such as heart disease, heart attacks, and strokes.
- Xanthomas: Xanthomas are fatty deposits that can develop under the skin or in internal organs of dogs with hyperlipidemia. These yellowish, raised nodules are typically found on the skin and can be itchy or painful for the dog. While xanthomas themselves may not be life-threatening, they are a visible sign of high cholesterol and can be an indicator of the potential for other complications.

Hyperlipidemia and Breed Predisposition
Certain dog breeds are more prone to hyperlipidemia. It’s essential for owners of these breeds to be vigilant and proactive in managing their dog’s health. Some of the breeds that appear to be affected more are:
- Miniature Schnauzers
- Beagles
- Shetland Sheepdogs
- Dobermanns
- Rottweilers
- Pyrenees Mountain Dogs
Preventing Hyperlipidemia
Preventing hyperlipidemia involves maintaining a healthy lifestyle for your dog. This includes a balanced, low fat diet, regular exercise, and weight management. Avoiding high-fat treats and maintaining a close relationship with your veterinarian are key in preventing this condition.
High Cholesterol in Dogs – Final Thoughts
Hyperlipidemia, or high cholesterol, is a condition that can affect dogs, impacting their overall health and well-being. Recognizing the signs, seeking early diagnosis, and following your veterinarian’s guidance for treatment and management are crucial steps in providing the best care for your pup.

FAQ about High Cholesterol in Dogs
Can high cholesterol in dogs be genetic?

Yes, high cholesterol in dogs can be genetic. Just like humans, dogs can inherit certain health conditions from their parents, including high cholesterol. This means that if a dog’s parents have high cholesterol, there is a higher likelihood that the dog will also develop this condition.
Are there specific dog foods designed for dogs with high cholesterol?

Specific dog foods designed for dogs with high cholesterol do exist. These specialized diets typically include low-fat and low-cholesterol ingredients, such as lean proteins and healthy fats. They may also contain added supplements like omega-3 fatty acids, which can help improve cholesterol levels.
Can hyperlipidemia in dogs be completely cured?

Hyperlipidemia in dogs cannot be completely cured, but it can be managed with proper treatment and lifestyle changes. Treatment typically involves a combination of dietary modifications, exercise, weight management, and medication to control lipid levels.
What are the dangers of untreated hyperlipidemia in dogs?

The dangers of untreated hyperlipidemia in dogs can be significant. High levels of lipids in the blood can lead to the formation of fatty deposits in the arteries, which can increase the risk of heart disease, stroke, and other cardiovascular problems. Untreated hyperlipidemia can also cause pancreatitis, a painful inflammation of the pancreas. Additionally, it can lead to liver disease and other complications. It is vital to diagnose and treat hyperlipidemia in dogs to mitigate these potential health risks.
How often should I have my dog’s cholesterol levels checked?

The frequency at which you should have your dog’s cholesterol levels checked depends on their individual health and risk factors. Generally, it is recommended to have a baseline cholesterol test done when your dog is young and healthy. After that, regular check-ups are advised for dogs with underlying health conditions or those on medications that may affect cholesterol levels. Your veterinarian can provide specific guidance based on your dog’s needs and medical history.